DESCRIPTION: ACETYL CHLORIDE IS A CLEAR, CORROSIVE AND FUMING LIQUID; MELTING POINT OF –112℃, BOILING POINT OF 51-52℃, REFRACTIVE INDEX OF 1.3890. IT UNDERGOES VIOLENTLY HYDROLYSIS IN PRESENCE OF ATMOSPHERIC MOISTURE. IT IS SOLUBLE IN ETHER, ACETONE, AND ACETIC ACID. IT IS PREPARED BY REACTING ACETIC ACID WITH A HALOGENATING AGENT SUCH AS PHOSPHORUS (III OR V) CHLORIDE OR SULPHUR DICHLORIDE OXIDE. IT IS WIDELY USED AS AN ACETYLATING AGENT IN THE SYNTHESIS OF FINE CHEMICALS, AGROCHEMICALS AND PHARMACEUTICALS. THE HYDROGEN ATOMS REPLACE OXYGEN ATOMS IN ALCOHOLS OR NITROGEN ATOMS IN AMINES, WHICH PROTECTS AMINE GROUPS DURING AMINO ACID SYNTHESIS. IT IS ALSO USED AS AN INTERMEDIATE FOR DYES. IT IS ALSO USED TO DETERMINE WATER IN ORGANIC LIQUIDS AND IN TESTING CHOLESTEROL.
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